Toxic leukoencephalopathy
From Radipedia
Toxic leukoencephalopathy is an alteration of cerebral white matter in which mylin sufferes the majortity of damage. This can be caused by a wide variety of toxins including chemotherapy, drugs of abuse (EtOH, coke, heroin), and carbon monoxide. [1] Similar finding can also be found with demyelinating diseases like multiple sclerosis, a variety of metabolic disorders, and cerebrovascular disease.
Cases have been published describing cocaine induced encephalopathy [2] as was the case in these images.
Differential Diagnosis
Acute Multiple sclerosis enhances with gadolinium while toxic leukoencephalopathy does not.
