Posttransplant lymphoproliferative disorder

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Renal Transplant and Colonic Thickening
Renal Transplant and Colonic Thickening

Ebstein-Barr virus (EBV) infects lymphoid cells in immunosuppressed transplant patient and causes unregulated expansion of lymphoid cells.


  • Range from lymphoid hyperplasia to malignant lymphoid proliferation
  • Presents as adenopathy, fever, malaise
  • Can involve, CNS, chest, abdomen, etc


Differential in Patient A

  • Graft versus host diseases (GVHD)
  • Colitis


Case was path proven PTLD