Patterns of Cardiac MRI Enhancement

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Non-ischemic Cardiomyopathies

Hypertrophic Cardiomyopathy (HCM) - 80% demonstrate LGE, often involving the regions of hypertrophy, junctions of the interventricular septum and the RV free wall

Anderson-Fabry - LGE of the inferolateral wall at the basal level

Amyloidosis - global hypertrophy, often involving the right ventricle, thickening of the interatrial septum and of the atrial walls, diffuse subendocardial LV hyperenhancement

ARVD - progressive RV failure, frequent arrhythmias, RV dysfunction can be assess with cMR, but fatty infiltration of RV wall is difficult and often leads to misdiagnosis.

Sarcoidosis - patchy hyperenhancement along the epicardium or mid-myocardium, basal and septal involvement is frequent. Approximately 10-30% of patients demonstrate a subendocardial or transmural hyperenhancement pattern that mimics CAD.

Mahrholdt et al Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies