Panlobular emphysema

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Lower lobe dominant emphysema from A1AT
Lower lobe dominant emphysema from A1AT
  • Uncommon
  • Associated with Alpha 1 anti trypsin deficiency and IV methylphenidate (Ritalin)
  • Inflated hyperlucent lungs
  • Diffuse or lower lobe predominance
  • Small vessels
  • No focal areas of lung destruction or bullous lesions as in Centrilobular emphysema