Osteosarcoma

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OsteoSarcPA.jpg
OsteoSarcLat.jpg
OsteosarcBoneScan.jpg
OsteoSarc.MRIs.jpg
OsteoSarc.MRIa.jpg

Conventional osteosarcoma (85%)

  • Intramedullary mass, extends through cortex
  • Sunburst periosteal reaction


Telangiectatic osteosarcoma (< 5%)

  • Lytic lesion with cystic cavities


Multicentric osteosarcoma (1%)

  • Multiple sites (usually symmetric)
  • Only in children (5-10 years)
  • Extremely poor prognosis


Parosteal osteosarcoma (3%)

  • Older age group (20 - 50 years)
  • Classically posterior distal femur
  • Attached to underlying cortex at origin (broccoli appearance on CT)


Periosteal osteosarcoma (1%)

  • Intermediate-grade
  • Diaphyseal
  • No medullary involvement
  • Cortical thickening


Gnathic osteosarcoma (5-9%) Originates in mandible or maxilla


Secondary osteosarcoma (5%)

  • Association with Paget disease, prior radiation, bone infarct, etc


Differential

  • Myositis ossificans - ossifies from out to in (lucent center) unlike osteosarcoma