MRI spectroscopy

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Creatine and Phosphocreatine (Cr) - cellular energy metabolism

Choline (Cho) - cell membrane synthesis, marker of cell turnover, increased with neoplasms or inflammation

N-acetyl aspartate (NAA) - marker of neuronal integrity, depleted in diseases that destroy or replace neurons

Lactate - not in normal spectrum, but may be present with inflammation, infarction and some neoplasms

Myoinositol - marker for Alzheimer disease


Malignancy

  • Increases NAA
  • Cr decreases
  • Choline, lactate and lipids increase