Invasive ductal carcinoma

Invasive Ductal Carcinoma Not Otherwise Specified (IDC NOS)

• IDC NOS and Ductal carcinoma in situ (DCIS) account for 85% of breast cancers
• IDC NOS presents as a spiculated or irregular mass or as a new focal asymmetry

Well Differentiated Subtypes of IDC

• Overall better prognosis than IDC NOS
• Mucinous
  • Low density oval, circumscribed mass containing mucin
  • High T2 signal on MRI
• Medullary
  • Round mass with ill defined boarders
  • Well circumscribed carcinoma composed of poorly differentiated cells with scant stroma and prominent lymphoid infiltration
• Tubular
  • Appears spiculated
  • Excellent prognosis (tubular = cool)
• Papillary
  • Round intraductal or intracystic mass
  • Often present with nipple discharge

Poorly Differentiated IDC

Previous MLO	Previous CC
Current CC	Mag CC	Current MLO	Mag MLO
US Mass	US Mass	US Axilla
Staging CT	Staging CT