Acute cholecystits is caused by gallstones in the gallbladder resulting in inflammation of the GB wall and potentially ischemia and infection. Patients present with pain, right upper quadrant tenderness, and leukocytosis. About 70% of patients with acute cholecystitis have diffuse wall thickening.
Major Criteria for Acute Cholecystitis - Gallstones, Sonographic Murphy's sign
Minor Criteria for Acute Cholecystitic - Wall thickening > 3 mm, Pericholecystic fluid
Differential Diagnosis for GB Wall Thickening (neither sensitive nor specific for cholecystitis)