C-ANCA disease

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aka Wegener's Granulomatosis

  • Necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts and kidneys
  • Autoimmune in nature of unknown cause
  • Prediliction for males in 50's.

  • Multiple sharply marginated nodules or masses
  • Irregular, thick-walled cavitary lesions may be seen during the course of disease
  • Localized and diffuse areas of air-space opacification may also be seen, representing either hemorrhage or pneumonia