Bronchogenic carcinoma
From Radipedia
- Leading cause of cancer death
- Non-surgical disease at IIIB and worse, i.e. T4 or N3 makes case non-surgical
Adenocarcinioma (50%)
- Peripheral location
- Weakest association with smoking
- Can arise from scar, scar carcinoma
- Subtype Bronchoalveolar cell carcinoma (BAC)
Squamous Cell Carcinoma (30%)
- Central location
- Cavitation can occur
- Strong smoking association
- Fast growing
- In young non-smokers, may be related to HPV and papillomatosis
Small Cell (15%)
- Central perihilar mass
- Paraneoplastic syndrome
- SVC syndrome
- Grows fast, spreads early
Large Cell (5%)
- Large, peripheral
Also
- Bronchial carcinoid makes up 90% of lung low grade malignancy
- Pulmonary lymphoma - often in immunocompromised